Stephen Mohan has joined Calastone as chief operating officer from DST, where he was most recently executive director of transformation and innovation.
Mr Mohan will be responsible for Calastone's UK and European business, as well as leading the firm's global operational functions including product development and service delivery.
He has previously held roles at bank of New York, M&G and Cofunds.
Calastone global chief executive Julien Hammerson said, "With over 20 years’ experience in the market, Stephen has a proven track record in delivering significant growth at speed and scale for successful financial services businesses, specifically within the mutual funds sector, and I look forward to working with him as we continue to extend our reach across major global financial markets."