Mr Adams worked at NAB for 17 years and held numerous senior positions with the bank before leaving to join the technology sector in a consulting capacity.
APRA chairman Wayne Byres said Mr Adams will be a welcome addition to the regulator’s team.
“Mark brings to APRA valuable commercial experience across a range of business activities, and a strong commitment to serving the Australian community by ensuring a sound and well-managed financial system,” he said.
Mr Adams replaces Ben Gully, who stood down from the role to return to Canada for personal reasons.