La Trobe's new Hong Kong office will be headed by group executive director for Asia-Pacific Hung Fei Chan.
Mr Chan, who joined La Trobe in 2013, said the new office would complement the company's existing office in Shanghai.
La Trobe established operations in Shanghai in 2009 and also set up in the Shanghai Free Trade Zone in 2014.
Greg O'Neill, president and chief executive of La Trobe, said, "Hong Kong and Asia are a key pillar of our international strategy, allowing us to tap into the world’s fastest growing economic region.
"This is the right time to open an office in Hong Kong. Mr Chan’s firsthand experience on the ground and network throughout Asia has played, and will continue to play a pivotal role to the organisation’s shape and future expansion into the Asian region."